Safe Houses are social hubs and fast travel locations to allow players to interact with each other and to refill on ammo and supplies. There is a Safe House in almost every district in Manhattan. There are two basic types of safe house: those in Manhattan and those in the Dark Zone.

Normal Safe Houses are locations set up and manned by the JTF to provide localized support to personnel in the field, as well as basic/temporary shelter for some civilians. Safe houses serve as a base of operations for each district; each one is a safe zone, which means that weapons and skills are disabled. Unlike the outside world, players can see other players that are not members of their group. Players can recruit one other from these Safe Houses either by selecting them in person, or using a matchmaking terminal present.

Each normal Safe House contains a re supply crate that refills ammo, frag grenades, and medkits for free. The player's stash can also be accessed. Additionally, every normal safe house has either a gear vendor or weapon vendor. As well, all safe houses have a situation board which will place all encounters for that district on the player's map. Finally, there is also a JTF Officer that serves as your guide for side missions within that district. Upon completion of all side missions in that district, the officer will give the player an extra reward.

There are also safe zones within the Dark Zone, though they are run by individual private citizens rather than the JTF. Unlike normal safe houses, they have only a vendor and resupply box. The vendor sells Dark Zone items. Also unlike normal safe houses, Dark Zone safe houses have multiple entrances and exits to discourage players from griefing one another.

District Level Safe House Location Vendor JTF Officer
Hudson Yards 5-9 Kerman Station West 34th St and Hudson Blvd East Weapons JB Keller
Garment District 5-9 The Cavern West of West 34th St and 7th Ave Gear Brycce Thompson
Tenderloin 9-12 The Meat Locker East of West 24th St and 7th Ave Weapons Simon Kapornick
Hell's Kitchen 10-13 Dante's Run East of West 42nd and 10th Ave Gear Kelly Garcia
Time's Square 10-14 Autumn's Hope East of West 49th St and Broadway Ave Gear Winston Jefferson
Clinton 14-15 Wolves Den Southeast of West 52nd St and 9th Ave Weapons Sammy O'Hara
Flatiron 15-16 Madison's Stand East 29th St and Madison Ave Gear Anthony Zappa
Gramercy 16-18 The Last Call West of East 20th st and 1st Ave Weapons Suzie Broughn
Stuyvesant 18-19 The Ward South of East 23rd St and Avenue C Gear
Kips Bay 20-23 Southpaw Northwest of East 29th St and 1st Ave Gear Paul Aguilar
Murray Hill 24-26 Grindhouse West of East 38th St and 3rd Ave Weapons Albert Gutnick
Turtle Bay 27-28 The Firewall East 43rd St and 2nd Ave Gear Lissa Montelli
Midtown East 28-30 The Crypt East of East 52nd St and Madison Ave Weapons Teresa Lopez

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